I discovered this is the course of beta testing drivers for another RIP. No big deal because I was going to make a new calibration and profile anyhow for that substrate. And what I have been testing is what color quality difference if any can be seen with ink limits per channel and linearization done with the RIP when by-passing the printer calibration vs. using the printer calibration only and creating the profile on top of that with other profile creation software. Testing to see if it is easier to just re-calibrate on the printer as opposed to re-linearization with the RIP after a head change etc.
But this would apply to all RIPs. If the print mode is gone then I am sure would get a error, and if you re-calibrated then that would be gone as well and be set to what ever was in the download, which may or not be the same thing that was in the original.
Best to make sure you have download the Profiles from the printer and save them somewhere if you did the profiling on the printer. If you profiled from the RIP you should have the profiles saved somewhere. I would think all RIPs would save the downloaded profiles somewhere but without checking each RIP I do not know how each one handles that. The question is what happens to the calibration. I suppose that would be saved in an oms file that could be imported back into the printer. I don't know that any RIPs save the calibration info and if they did could it even be sent back to the printer. Also not sure if you by pass the calibration on the printer how the RIPs handle ink limits per channel and linearization as to what is sent back to the printer. I do know in testing Caldera it seemed to send this and the profile back to the printer. Not really sure how you would test this for calibration. With Onyx there seems to be no way to send this back to the printer. I have a demo sitting here of Colorgate that I have yet to try and am not sure I will even try. The beta testing I am doing right now has some interesting aspects to it that really are working nice and makes Onyx and Caldera seem like a royal PITA.
Best case practice I think for all downloaded profiles is to clone them and save them with a new unique name so that if you add print modes and make any other changes that they won't be overwritten if you happen to download another profile with the same name. This also would a good thing to do for all custom substrate you create just in case you happen to download a profile with the same name.