You'd only be able to use basic interfaces - virtually all plotters use variants of hpgl - they just add extras to it.
If you use an older driver, you can't use things like barcode scanners or auto alignment - if the highest version driver supported it, you might have a chance, but it's basically the lowest common denominator.
I have had luck with modifying some drivers, but it's not guaranteed to work. All depends on if they've rewritten them, or just updated them.