Hey Evie, we had the same delima 6 months ago when trying to decide the best setup for our needs.
We went through signwarehouse.com to get our Mutoh 1204, Q54, Flexi 10 package. It was a great deal and came in at the top of our budget of $13k, we paid cash and got lots of extra thrown in. So far our mutoh has printed great and the Q54 is a good match after 6 months.
We were looking at 3 printers/cutters, the roland sp-300i, mamaki cjv-100 and the mutoh 1204 SW package. When the wife told me "to just pick one!" the mutoh just fit our needs better. The 300i was much slower printing and cutting and max print/cut width is 29". I did not want to limit ourselves to 29" and I know we would need something wider and got fed up with the "wholesalers". The mamiki seemed like a really great machine, ink, parts, support the downfall is the odd 40" width. Then there is the Mutoh 1204, it prints faster then the other two, it cuts faster then the other two, and I can print on one machine and cut something else on the other. Most media is in a 54" or a 30" and the 48" is an odd size too. I call SW to get our rolls cut done if needed at $10.00 a cut. I also think the wave printing feature on the mutoh is great. I have yet to print something and say anything bad about the quality.
I think the major difference ( correct me if I'm wrong) is that Mutoh has more plastic in their printers. Our is built really well but I'm sure whatever you choose you will no go wrong. Oh and make sure you have a good support plan, your going to need it until you get the hang of things. Good luck!