I also have the 250GT and there are a few things you need to keep in check to prevent this. It also (from time to time) just happens, and you have to clean up the over-spray afterwards.
Our Oce 250GT lives on printing ACM and corflute.
When using ACM, I find a screw driver or something metal with a rubber handle to get rid of the static. It's pretty cool in the dark as you get to see the big blue flash it creates!
Corflute is a different beast. It's amazing just how battery like that plastic is when it comes to storing energy. Running the heads as close as possible to the media is critical. I use a precision digital caliper to measure all four corners after making sure there are no bunny ears. I take an average and use that as the head height making sure vacuum is above 15kpa.
Our corflute is delivered in clear plastic bags which we load on a shelf and simply pull from the stack when required. This generates a lot of static, so the anti-static bar for us is essential. It works well compared to when it is turned off, especially on ACM.
On 3.3mm corflute, the height usually comes out at 3.35 or 3.28.
ACM and Palite is more precise I found. 3mm palite and ACM I typically run at 3.10 or 3.05.
Your heads are also about 1.3mm above your media by default. So if you set it to 0mm in the printer controls, the heads are still going to be 1.3mm above the table. This means if you are conservative with your head height and enter 4.0mm for a 3mm substrate your heads are that much higher off the table leaving them susceptible to static from the platen which leads to ink drops and over-spray on the media.
Hope this helps.