210's a little bit nastier to apply with the big squeegee due to the thin backing on it.
Dale posted a few techniques on a thread regarding it a little while back at the following thread.
http://www.signs101.com/forums/showthread.php?t=65006
Basically you will need to pull the backing from the laminate as you push the squeegee, if you push the squeegee too far ahead it will fold/flip the laminate over due to the thinner backing and possibly create air bubbles where it creases. Dale suggests applying a transfer tape to the back to harden up the backer a bit more, I use Oracal 210 mainly because it's inexpensive though, so adding cost to it doesn't really work with my business. I'm thinking about switching over to 3M cast though and charging premium price for premium materials, still on the fence between primarily using it or 3951/290.
So there's a little bit more technique and learning for the 210 laminate. I honestly haven't used the BS for any other kind of laminate, but others report better results, and for applying vinyl to substrate the BS's awesome. Definitely worth the money, just be prepared for a little extra learning on 210.