I use a XR-640 with Versaworks and build artwork with Adobe CC.
You don't need to use a custom pallete provided by Roland, but just remember the 100% Cyan named "PerfCutContour" and 100% Magenta named "CutContour"
I always pay attention to the "perf" and "normal" cut lengths in VW Advanced Cut Controls cause they really do count. For large perf projects, you need enough "tab" material to hold the print in place so it wont fall out.
and please please- make sure you have enough blade extension on your cutter(and not too much). Hold the exposed tip to the finished media thickness- you want just the tip of the blade to be a hair over the thickness of the media, and be gentle on cutting pressure. The most common mistake is having too much of the blade exposed. While you may enjoy nice cuts in the beginning, your cutting strip will fail sooner, dull you blade even faster, and make you second guess your pressure settings and may spoil the cut.