my cure for wrinkles is a two-step process:
1) set a proper "web"
2) using cotton gloves, I wipe my print from center>outward left/right as the laminator operates. Removes any random debris AND helps keep the "flow" of your sheet moving outward as it travels into the rollers.
I also laminate as 50lbs of pressure, which is basically the lowest setting. Anytime I've dialed it up higher, wrinkles appear more often.