Hrmm... it's funny that the dot pattern doesn't seem affected at all. If it is the data issue I mentioned, you'd be able to tell right away, as the number of passes would change, and your print might actually be elongated.
If this still happened randomly with the TIFF, my best guess at this point is something in your ink feed, be it in the cartridge assembly, lines, dampers, or manifolds. Did the problem go away entirely with the TIFF though, and is only appearing in the EPS?
Sorry about the late answer.
We'll change two heads tomorrow (BK and LC) and see what happens. Thare are so many problems with the machine right now, that I'm happy that it prints at all.