So, make sure that you disable Windows defender Firewall and set User Account Control to Never Notify for the install. You can turn them back on afterwards, but will probably need to configure the firewall with Gerber as an exception so that it can communicate with the output devices and the security key.
Are you installing from a disk that came from Gerber or from a download from Gerber? For windows 10 you need Omega 6.5.0.95 - which, last I knew, only came as a
download from Gerber. The version on the disk will work with earlier versions of Windows.