I have one of the 1st gen Wacom Cintiq tablets, so it runs 8.1 Pro.
It handles CS6 Master Suite and my various digitizing programs. It's quite a bit more, but I also use it as my travel/backup work computer.
Of course, if CrossOver goes from Beta to Stable, it could be possible to even use a chrome based tablet for full Windows programs. Specs would probably kill the experience though, but it may be possible at some point.