Do you mean for search engine optimization? As in rather then calling the photo, photo6.png call it vehiclegraphics.png ?
I mean the alt tags, but yes, you should also name the file contextually for search. And not generically, use keywords you're targeting.
Filename: coke-trailer-wrap.jpg
HTML: <img src="/images/coke-trailer-wrap.jpg" alt="Coke Trailer Wrap" />
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