Your RIP will do a far better job interpreting RGB than any other software you or anyone else has.
Here's why, sort of...
When you convert a bitmap from RGB to CMYK, regardless of what software you might be using, each pixel is mapped from its RGB value to some arbitrary CMYK value. One by one.
When a RIP maps an RGB bitmap ultimately into CMYK for printing AND you're properly printing at a higher printer resolution than the bitmap resolution, at least 4 to 1 being optimum, then [assuming for this exposition a 4:1 printer to bitmap resolution ratio] each bitmap pixel is mapped into 16 printer pixels. A process, referred to as 'dithering', then allocates each of the 16 printer pixels to some CMYK value in an attempt to use those 16 pixels together to better reproduce the original RGB value of the bitmap pixel. A good dithering algorithm with sufficient room can hit colors not normally seen in the CMYK spectrum but common to RGB.
In other words, when you let the RIP deal with it, it has a lot more to work with.