tiff is ok with layers. do not ever print pdf with versaworks.
I wouldn't say that exactly. You just better know what is *IN* that PDF and how it was built.
What would I have to watch out for with PDF? I have had some goofy stuff with PDFs that were not layered or complicated in any way. One I remember had a gradient, but the image was a tiff inside the pdf. The gradient was goofed.