We have 2 Seiko 64s and a HP 9000 & 10000s. They have been work horses for us. They do need to be vented though, gets very irritating smelling the solvent. The Seiko inks are a little bit cheaper than the HP inks it seems (everywhere we have went they were) When using the OEM inks the prints are awesome (we only have OEM ones so I can't speak for other 3rd party inks). The Seiko uses a SCSI connection while the HP uses a USB one. The amount of different medias it prints on is very nice and it does nicely on thicker materials. If you buy one however, spend the money to get it profiled correctly or learn yourself. Not one of them printed the way it should have using any stock profiles. Other than that, they will print as fast as you can feed rolls of material.