I was fortunate to have worked at a national sign company with several locations. The corporate adaption of the lean manufacturing concept was ingrained in us as manager's and then we taught and trained our departments on its methods. This applied from the offices to the plant floor. It does work, but you have to take the principles and adapt them to your situation. Most of it is instinctive and common sense anyway.
The quick explanation of a 5 S is from the 5 Japanese words which mean: Sort, Set in Order, Shine, Standardize, Sustain. It works in a small shop, plants, hospitals, offices. If I could sum it up for you:
Get rid of any clutter & anything that does not have a contributing function to your organization. Junk, scrap, equipment etc. This is the HARD part because of the "I'll use it some day..." thinking.
Organize everything else based on job function. What's needed, how many, where to locate. Everything has a place. Then you label and mark everything. Peg boards, bins, hangers, etc. When you need it you know exactly where to go.
Clean up everything. No dirt, no clutter, all the brass shines, all the chrome shines, the floor is shined. A one time gang buster of a cleaning. The principle is " You want a first class place to come to work". Even if it is in your garage.
Everything is now "set" so you standardize your process. Do the same thing over and over. Tools in location, no clutter, established processes are followed repeatedly every day.
Sustain the entire concept.
Hope I didn't bore you.