Well, maybe if hand painting is out of your wheelhouse and you wanted to "fake" hand painting (but then it just looks fake). I cringe when I see fake hand lettering, and I cringe even more when the fake lettering has fake alternative characters to make it look real (which makes it look even more fake). But I see it all the time with younger designers who wouldn't know which end of a brush to hold. The worst offenders are using typeset fake letters in comic book production - ewhhh! The big boys stll employ lettering artists!