Would stake my business on a Durst. (Con is the cost, only other machine we've had that would come close to reliability and consistency would be SwissQ).
I'm like you, I've had every smaller latex machine, 25500, 26500, 360, 570, 3000.
As for your situation, you might want to consider the HP Latex 1500 or 3000.
I run 200,000+sqft a month on my 3000. It has its pros and cons like most printers. You still have all the nuances or color consistency and tiling like other hp machines but you're going to have a lot more throughput and cheaper ink cost.